APHAR - Austrian Pharmacological Society - Österreichische Pharmakologische Gesellschaft

GENERAL INFORMATION ABSTRACTS TRAVEL INFORMATION HIGHLIGHTS
GART 2015 SCIENTIFIC PROGRAM SOCIAL EVENTS SPONSORS

21st Scientific Symposium of
the Austrian Pharmacological Society APHAR
Joint meeting with the British Pharmacological Society and the Pharmacological Societies of Croatia, Serbia and Slovenia
Celebrating the 20th Anniversary of APHAR
and the 25th Anniversary of EPHAR
Graz, Austria, 16–18 September 2015
SCIENTIFIC PROGRAM

← download the (preliminary) program
In the program below, abstracts with numbers starting with 'A' are published in Intrinsic Activity, 2015; 3(Suppl.2)
(abstract numbers link to the online publication).
Presentation numbers beginning with 'X' are unpublished presentations.

Download Poster PDF:
Size A4, A3, A2

WEDNESDAY – TALKS THURSDAY – TALKS FRIDAY – TALKS
WEDNESDAY – POSTERS THURSDAY – POSTERS FRIDAY – POSTERS

Oral Communications – Session 8
Chair: Bernd Jilma (Vienna)
08:00–08:15
→ X.11 Effect of artificial tears on tear film thickness in patients with moderate dry eye syndrome
Klemens Fondi, Doreen Schmidl, Leopold Schmetterer, Katarzyna J. Witkowska, Carina Baar, René M. Werkmeister and Gerhard Garhöfer (Vienna)
08:15–08:30
→ A2.27 Effects of testosterone treatment on hypothalamic microstructure in female-to-male transsexuals
Georg S. Kranz, Andreas Hahn, Ulrike Kaufmann, Martin Küblböck, Roland Sladky, Sebastian Ganger, René Seiger, Siegfried Kasper, Christian Windischberger and Rupert Lanzenberger (Vienna)
08:30–08:45
→ A2.28 Changes in progesterone levels correlate with changes in subcortical brain structures in male-to-female transgender subjects after acute high-dose cross-sex hormone administration
René Seiger, Andreas Hahn, Allan Hummer, Georg S. Kranz, Sebastian Ganger, Michael Woletz, Christoph Kraus, Ronald Sladky, Siegfried Kasper, Christian Windischberger and Rupert Lanzenberger (Vienna)
08:45–09:00
→ A6.1 Non-linear dose-dependent distribution of tariquidar to the human liver measured with PET
Beatrix Wulkersdorfer, Martin Bauer, Markus Zeitlinger, Maria Weber, Cécile Philippe, Johann Stanek, Sabine Strommer, Wolfgang Wadsak, Markus Müller and Oliver Langer (Vienna, Seibersdorf)
09:00–09:15
→ X.18 Outcome prediction of epilepsy surgery based on 10-min PET acquisition: pooled analysis of two European centres
Martin Bauer, Maria Feldmann, Rudolf Karch, Wolfgang Wadsak, Markus Zeitlinger, Markus Müller, Ekaterina Pataraia, Marie-Claude Asselin, Matthias J. Koepp and Oliver Langer (Vienna, Manchester)

09:15–09:45
Coffee break / Posters

Oral Communications – Session 9
Chairs: Brigitte Blöchl-Daum (Vienna) & Darko Modun (Split)
09:45–10:00
→ A1.1 Potent irreversible P2Y₁₂ inhibition does not reduce LPS-induced coagulation activation in a randomized, double-blind, placebo-controlled trial
Christian Schörgenhofer, Michael Schwameis, Eva-Luise Hobl, Cihan Ay, Nigel Key, Ulla Derhaschnig, Bernd Jilma and Alexander Spiel (Vienna, Chapel Hill)
10:00–10:15
→ X.7 Morphine decreases ticagrelor concentrations but not its effects: a randomized, double-blind, placebo-controlled trial in healthy volunteers
Eva-Luise Hobl, Birgit Reiter, Christian Schoergenhofer, Michael Schwameis, Ulla Derhaschnig, Thomas Stimpfl and Bernd Jilma (Vienna)
10:15–10:30
→ A3.2 Safety, pharmacokinetics, pharmacodynamics and immunogenicity of a new anti-TNFα monoclonal antibody (GSK2800528)
Iain McSherry, Malcolm Boyce, Stefano Zamuner, Tarjinder Sahota, Gareth Lewis, Bettina Cortezi, Katherine Davy, Mary Birchler, Juliet Reid, Patty Wolf, Bams Abila and Carol Routledge (London, Milton Keynes)
Plenary Lecture
10:30–11:30 Simon Day (London, UK)
“What constitutes ‘adequate evidence’? — from orphans to mega-trials”

11:30–13:00 Lunch break / → POSTER Session III

Plenary Lecture
Chair: Ljiljana Gojković-Bukarica (Belgrade) & Gunther Marsche (Graz)
13:00–14:00 Valery Bochkov (Vienna, Graz)
“New targets in cellular stress and inflammation: hints from lipid oxidation products”
Oral Communications – Session 10
14:00–14:15
→ A1.6 Resveratrol wine polyphenol relaxes rat renal artery in diabetic rats: The role of smooth muscle voltage-sensitive potassium channels
Ljiljana C. Gojković-Bukarica, Jasmina Marković-Lipkovski, Radmila B. Novaković, Sanja Ćirović, Jovana Rajković, Vladimir Đokić, Danilo Obradović and Helmut Heinle (Belgrade, Tübingen)
14:15–14:30
→ A1.13 Role of aldehyde dehydrogenase 2-catalyzed nitric oxide formation in nitroglycerin-induced vasorelaxation
Marissa Opelt, Michael Russwurm, Doris Koesling, Astrid Schrammel, John T. Fassett and Bernd Mayer (Graz, Bochum)
14:30–14:45
→ A1.10 Privileged ER Ca²⁺ refilling in vascular endothelial cells: evidence for a role of the Na⁺ / Ca²⁺ exchanger (NCX)
Cristiana M. L. Di Giuro, Klaus Groschner, Michaela Lichtenegger, Roland Malli, Brigitte Pelzmann, Niroj Shrestha, Cornelis van Breemen and Nicola Fameli (Graz, Vancouver)

14:45–15:00
Short break

APHAR & EPHAR Research Awards (with oral presentations)
Chair: Thomas Griesbacher (Graz) & Filippo Drago (Catania)
15:00–16:00 APHAR Hans Horst Meyer Award
Andreas Lieb (Innsbruck): “CACNA1D de novo mutations in autism spectrum disorders activate Ca_V1.3 L-type calcium channels”
APHAR Heribert Konzett Award
Eva Sturm (Graz): t.b.a.
EPHAR Young Investigator Award
Tamás Szél (Szeged): ”Abnormal repolarization as the basis for late potentials and fractionated electrograms recorded from epicardium in experimental models of Brugada syndrome“
EPHAR Young Investigator Award
Georg Kranz (Vienna): ”High-dose testosterone treatment increases serotonin transporter binding in transgender people“

Workshop “How to write great papers”
16:00–17:00
(parallel session) Jaap van Harten
Elsevier (Utrecht)
EPHAR Council Meeting
16:00–17:00
(parallel session) EPHAR Council Meeting
(Delegates nominated by EPHAR member societies, EPHAR Executive Committee and invited guests)

EPHAR Executive Dinner
19:30 (Invited guests only)

_________
03.08.2015

GENERAL INFORMATION	ABSTRACTS	TRAVEL INFORMATION	HIGHLIGHTS
GART 2015	SCIENTIFIC PROGRAM	SOCIAL EVENTS	SPONSORS

WEDNESDAY – TALKS	THURSDAY – TALKS	FRIDAY – TALKS
WEDNESDAY – POSTERS	THURSDAY – POSTERS	FRIDAY – POSTERS


	Oral Communications – Session 8
	Chair: Bernd Jilma (Vienna)
08:00–08:15 → X.11	Effect of artificial tears on tear film thickness in patients with moderate dry eye syndrome Klemens Fondi, Doreen Schmidl, Leopold Schmetterer, Katarzyna J. Witkowska, Carina Baar, René M. Werkmeister and Gerhard Garhöfer (Vienna)
08:15–08:30 → A2.27	Effects of testosterone treatment on hypothalamic microstructure in female-to-male transsexuals Georg S. Kranz, Andreas Hahn, Ulrike Kaufmann, Martin Küblböck, Roland Sladky, Sebastian Ganger, René Seiger, Siegfried Kasper, Christian Windischberger and Rupert Lanzenberger (Vienna)
08:30–08:45 → A2.28	Changes in progesterone levels correlate with changes in subcortical brain structures in male-to-female transgender subjects after acute high-dose cross-sex hormone administration René Seiger, Andreas Hahn, Allan Hummer, Georg S. Kranz, Sebastian Ganger, Michael Woletz, Christoph Kraus, Ronald Sladky, Siegfried Kasper, Christian Windischberger and Rupert Lanzenberger (Vienna)
08:45–09:00 → A6.1	Non-linear dose-dependent distribution of tariquidar to the human liver measured with PET Beatrix Wulkersdorfer, Martin Bauer, Markus Zeitlinger, Maria Weber, Cécile Philippe, Johann Stanek, Sabine Strommer, Wolfgang Wadsak, Markus Müller and Oliver Langer (Vienna, Seibersdorf)
09:00–09:15 → X.18	Outcome prediction of epilepsy surgery based on 10-min PET acquisition: pooled analysis of two European centres Martin Bauer, Maria Feldmann, Rudolf Karch, Wolfgang Wadsak, Markus Zeitlinger, Markus Müller, Ekaterina Pataraia, Marie-Claude Asselin, Matthias J. Koepp and Oliver Langer (Vienna, Manchester)
09:15–09:45	Coffee break / Posters
	Oral Communications – Session 9
	Chairs: Brigitte Blöchl-Daum (Vienna) & Darko Modun (Split)
09:45–10:00 → A1.1	Potent irreversible P2Y₁₂ inhibition does not reduce LPS-induced coagulation activation in a randomized, double-blind, placebo-controlled trial Christian Schörgenhofer, Michael Schwameis, Eva-Luise Hobl, Cihan Ay, Nigel Key, Ulla Derhaschnig, Bernd Jilma and Alexander Spiel (Vienna, Chapel Hill)
10:00–10:15 → X.7	Morphine decreases ticagrelor concentrations but not its effects: a randomized, double-blind, placebo-controlled trial in healthy volunteers Eva-Luise Hobl, Birgit Reiter, Christian Schoergenhofer, Michael Schwameis, Ulla Derhaschnig, Thomas Stimpfl and Bernd Jilma (Vienna)
10:15–10:30 → A3.2	Safety, pharmacokinetics, pharmacodynamics and immunogenicity of a new anti-TNFα monoclonal antibody (GSK2800528) Iain McSherry, Malcolm Boyce, Stefano Zamuner, Tarjinder Sahota, Gareth Lewis, Bettina Cortezi, Katherine Davy, Mary Birchler, Juliet Reid, Patty Wolf, Bams Abila and Carol Routledge (London, Milton Keynes)
	Plenary Lecture
10:30–11:30	Simon Day (London, UK) “What constitutes ‘adequate evidence’? — from orphans to mega-trials”

11:30–13:00	Lunch break / → POSTER Session III

	Plenary Lecture
	Chair: Ljiljana Gojković-Bukarica (Belgrade) & Gunther Marsche (Graz)
13:00–14:00	Valery Bochkov (Vienna, Graz) “New targets in cellular stress and inflammation: hints from lipid oxidation products”
	Oral Communications – Session 10
14:00–14:15 → A1.6	Resveratrol wine polyphenol relaxes rat renal artery in diabetic rats: The role of smooth muscle voltage-sensitive potassium channels Ljiljana C. Gojković-Bukarica, Jasmina Marković-Lipkovski, Radmila B. Novaković, Sanja Ćirović, Jovana Rajković, Vladimir Đokić, Danilo Obradović and Helmut Heinle (Belgrade, Tübingen)
14:15–14:30 → A1.13	Role of aldehyde dehydrogenase 2-catalyzed nitric oxide formation in nitroglycerin-induced vasorelaxation Marissa Opelt, Michael Russwurm, Doris Koesling, Astrid Schrammel, John T. Fassett and Bernd Mayer (Graz, Bochum)
14:30–14:45 → A1.10	Privileged ER Ca²⁺ refilling in vascular endothelial cells: evidence for a role of the Na⁺ / Ca²⁺ exchanger (NCX) Cristiana M. L. Di Giuro, Klaus Groschner, Michaela Lichtenegger, Roland Malli, Brigitte Pelzmann, Niroj Shrestha, Cornelis van Breemen and Nicola Fameli (Graz, Vancouver)
14:45–15:00	Short break
	APHAR & EPHAR Research Awards (with oral presentations)
	Chair: Thomas Griesbacher (Graz) & Filippo Drago (Catania)
15:00–16:00	APHAR Hans Horst Meyer Award Andreas Lieb (Innsbruck): *“CACNA1D* de novo mutations in autism spectrum disorders activate Ca_V1.3 L-type calcium channels”**
	APHAR Heribert Konzett Award Eva Sturm (Graz): t.b.a.
	EPHAR Young Investigator Award Tamás Szél (Szeged): ”Abnormal repolarization as the basis for late potentials and fractionated electrograms recorded from epicardium in experimental models of Brugada syndrome“
	EPHAR Young Investigator Award Georg Kranz (Vienna): ”High-dose testosterone treatment increases serotonin transporter binding in transgender people“

	Workshop “How to write great papers”
16:00–17:00 (parallel session)	Jaap van Harten Elsevier (Utrecht)
	EPHAR Council Meeting
16:00–17:00 (parallel session)	EPHAR Council Meeting (Delegates nominated by EPHAR member societies, EPHAR Executive Committee and invited guests)

	EPHAR Executive Dinner
19:30	(Invited guests only)