APHAR - Austrian Pharmacological Society - Österreichische Pharmakologische Gesellschaft

GENERAL INFORMATION ABSTRACTS TRAVEL INFORMATION HIGHLIGHTS
GART 2015 SCIENTIFIC PROGRAM SOCIAL EVENTS SPONSORS

21st Scientific Symposium of
the Austrian Pharmacological Society APHAR
Joint meeting with the British Pharmacological Society and the Pharmacological Societies of Croatia, Serbia and Slovenia
Celebrating the 20th Anniversary of APHAR
and the 25th Anniversary of EPHAR
Graz, Austria, 16–18 September 2015
SCIENTIFIC PROGRAM

← download the (preliminary) program
In the program below, abstracts with numbers starting with 'A' are published in Intrinsic Activity, 2015; 3(Suppl.2)
(abstract numbers link to the online publication).
Presentation numbers beginning with 'X' are unpublished presentations.

Download Poster PDF:
Size A4, A3, A2

WEDNESDAY – TALKS THURSDAY – TALKS FRIDAY – TALKS
WEDNESDAY – POSTERS THURSDAY – POSTERS FRIDAY – POSTERS

09:15–09:30
Opening of the meeting
Thomas Griesbacher (Graz)
Oral Communications – Session 1
Chairs: Ákos Heinemann (Graz)
09:30–09:45
→ A1.14 Adenosine kinase mediates adenosine attenuation of cardiomyocyte microtubule cytoskeletal densification
John T. Fassett, Ping Zhang, Graciela Sala-Newby, Christine Hospach, Yingjie Chen and Bernd Mayer (Graz, Minneapolis, Bristol)
09:45–10:00
→ A1.9 Anti-addiction drug ibogaine and the heart: a delicate relation
Lena Rubi, Daniel Eckert, Michael Kovar, Vaibhavkumar S. Gawali, Hannes Todt, Stefan Boehm, Walter Sandtner, Xaver Koenig and Karlheinz Hilber (Vienna)
10:00–10:15
→ A1.7 Investigation of the antifibrillatory drug interactions between valsartan and diltiazem in isolated perfused rabbit hearts
Abdulrahman A. Almotrefi and Mohammad S. Alhumayyd (Riyadh)
10:15–10:30
→ A1.12 Cardiac dysfunction in adipose triglyceride-deficient mice: role of the ubiquitin–proteasome system
Marion Mussbacher, Heike Stessel, Gerald Wölkart, Guenther Haemmerle, Rudolf Zechner, Bernd Mayer and Astrid Schrammel (Graz)
10:30–10:45
→ A1.16 Doxorubicin nanoparticles conjugated with N-(2-hydroxypropyl)methacrylamide exhibit low cardiotoxicity in rats
Marko Vasić, Olivera Šarenac, Maja Losić, Hoay Yan Cheah, Lik Voon Kiew, Lip Yong Chung, Maria J. Vicent, David Murphy and Nina Japundžić-Žigon (Belgrade, Bristol, Kuala Lumpur, Velencia)

10:45–11:15
Coffee break / Posters

Plenary Lecture
Chair: Anna Bucsics (Vienna)
11:15–12:15 Andrew Brown (GSK, Stevenage, UK)
“Receptors for free fatty acids: emerging therapeutic targets?”

12:15–13:45 Lunch break / → POSTER Session I

Oral Communications – Session 2
Chair: Peter Holzer (Graz)
13:45–14:00
→ A2.5 K_V7 channels: potential targets for antinociceptive action of paracetamol
Sutirtha Ray, Isabella Salzer and Stefan Boehm (Vienna)
14:00–14:15
→ X.15 New explanations for an old drug: effects of the paracetamol metabolite NAPQI on neurotransmitter transporters
Derya Erdem, Jürgen Alphonsus, Peter Hasenhütl, Tina Hofmaier, Marion Holy, Anton Luf, Rainer Schmid, Walter Sandtner, Harald H. Sitte and Oliver Kudlacek (Vienna)
14:15–14:30
→ A2.25 Role of the central kappa opioid system in modulation of salt appetite through central and basolateral amygdala
Olivera Šarenac, Nina Japundžić-Žigon and David Murphy (Bristol, Belgrade, Kuala Lumpur)
14:30–14:45
→ A7.2 A pharmacological and computational study on sewarine, a naturally derived alkaloid, as a new ligand interacting with the κ opioid receptor
Aquilino Lantero, Michael Mairegger, Muhammad F. Asim, Elena Guerrieri and Mariana Spetea (Innsbruck)
14:45–15:00
→ A2.14 The G protein-biased kappa opioid receptor agonist 6′-GNTI blocks hippocampal paroxysmal discharges without inducing aversion
Luca Zangrandi, Johannes Burtscher and Christoph Schwarzer (Innsbruck)

15:00–15:30
Coffee break / Posters

Oral Communications – Session 3
Chair: Reiner Fischer-Colbrie (Innsbruck)
15:30–15:45
→ A2.4 Transient receptor potential ankyrin 1 channels participate in somatic pain hypersensitivity in experimental colitis
Piyush Jain, Romina Nassini, Serena Materazzi, Duccio Rossi Degl’Innocenti, Francesco De Logu, Camilla Fusi, Ahmed M. Hassan, Raphaela Mayerhofer, Florian Reichmann, Pierangelo Geppetti and Peter Holzer (Florence, Graz)
15:45–16:00
→ X.14 Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptors and increased colonic opioid sensitivity
Ulrike Taschler, Thomas O. Eichmann, Franz P. W. Radner, Gernot F. Grabner, Heimo Wolinski, Martin Storr, Achim Lass, Gunther Marsche, Ákos Heinemann, Rudolf Schicho and Robert Zimmermann (Graz, Munich)
16:00–16:15
→ X.4 Role of TRPV1, substance P and NK₁ receptor genes in the botulinum toxin type A antinociceptive action in mice
Ivica Matak, Valeria Tekus, Zdravko Lacković and Zsuzsanna Helyes (Zagreb, Pécs)
16:15–16:30
→ A2.13 Oxidative phosphorylation in the healthy and in the epileptic mouse brain
Johannes Burtscher, Luca Zangrandi, Erich Gnaiger and Christoph Schwarzer (Innsbruck)

16:30–17:00
Break

Otto Loewi Memorial Lecture
17:00–18:30 Welcome Address: Josef Smolle (Rector, Medical University of Graz)
Introduction and Chair: Ákos Heinemann (Graz)
On the David Herzog Fonds: Peter Scherrer (Graz)
Francesca Levi-Shaffer (Jerusalem, Israel)
“The mast cells, the eosinophils and the allergic effector unit: the best pharmacological target for allergy”
Organised by the Medical University of Graz and the David Herzog Fonds of the universities of Styria

Welcome Reception
19:30 Reception by the Mayor of the City of Graz
Town Hall, Hauptplatz 1
Free for registered participants

_________
03.08.2015

GENERAL INFORMATION	ABSTRACTS	TRAVEL INFORMATION	HIGHLIGHTS
GART 2015	SCIENTIFIC PROGRAM	SOCIAL EVENTS	SPONSORS

WEDNESDAY – TALKS	THURSDAY – TALKS	FRIDAY – TALKS
WEDNESDAY – POSTERS	THURSDAY – POSTERS	FRIDAY – POSTERS

09:15–09:30	Opening of the meeting Thomas Griesbacher (Graz)
	Oral Communications – Session 1
	Chairs: Ákos Heinemann (Graz)
09:30–09:45 → A1.14	Adenosine kinase mediates adenosine attenuation of cardiomyocyte microtubule cytoskeletal densification John T. Fassett, Ping Zhang, Graciela Sala-Newby, Christine Hospach, Yingjie Chen and Bernd Mayer (Graz, Minneapolis, Bristol)
09:45–10:00 → A1.9	Anti-addiction drug ibogaine and the heart: a delicate relation Lena Rubi, Daniel Eckert, Michael Kovar, Vaibhavkumar S. Gawali, Hannes Todt, Stefan Boehm, Walter Sandtner, Xaver Koenig and Karlheinz Hilber (Vienna)
10:00–10:15 → A1.7	Investigation of the antifibrillatory drug interactions between valsartan and diltiazem in isolated perfused rabbit hearts Abdulrahman A. Almotrefi and Mohammad S. Alhumayyd (Riyadh)
10:15–10:30 → A1.12	Cardiac dysfunction in adipose triglyceride-deficient mice: role of the ubiquitin–proteasome system Marion Mussbacher, Heike Stessel, Gerald Wölkart, Guenther Haemmerle, Rudolf Zechner, Bernd Mayer and Astrid Schrammel (Graz)
10:30–10:45 → A1.16	Doxorubicin nanoparticles conjugated with N-(2-hydroxypropyl)methacrylamide exhibit low cardiotoxicity in rats Marko Vasić, Olivera Šarenac, Maja Losić, Hoay Yan Cheah, Lik Voon Kiew, Lip Yong Chung, Maria J. Vicent, David Murphy and Nina Japundžić-Žigon (Belgrade, Bristol, Kuala Lumpur, Velencia)
10:45–11:15	Coffee break / Posters
	Plenary Lecture
	Chair: Anna Bucsics (Vienna)
11:15–12:15	Andrew Brown (GSK, Stevenage, UK) “Receptors for free fatty acids: emerging therapeutic targets?”

12:15–13:45	Lunch break / → POSTER Session I

	Oral Communications – Session 2
	Chair: Peter Holzer (Graz)
13:45–14:00 → A2.5	K_V7 channels: potential targets for antinociceptive action of paracetamol Sutirtha Ray, Isabella Salzer and Stefan Boehm (Vienna)
14:00–14:15 → X.15	New explanations for an old drug: effects of the paracetamol metabolite NAPQI on neurotransmitter transporters Derya Erdem, Jürgen Alphonsus, Peter Hasenhütl, Tina Hofmaier, Marion Holy, Anton Luf, Rainer Schmid, Walter Sandtner, Harald H. Sitte and Oliver Kudlacek (Vienna)
14:15–14:30 → A2.25	Role of the central kappa opioid system in modulation of salt appetite through central and basolateral amygdala Olivera Šarenac, Nina Japundžić-Žigon and David Murphy (Bristol, Belgrade, Kuala Lumpur)
14:30–14:45 → A7.2	A pharmacological and computational study on sewarine, a naturally derived alkaloid, as a new ligand interacting with the κ opioid receptor Aquilino Lantero, Michael Mairegger, Muhammad F. Asim, Elena Guerrieri and Mariana Spetea (Innsbruck)
14:45–15:00 → A2.14	The G protein-biased kappa opioid receptor agonist 6′-GNTI blocks hippocampal paroxysmal discharges without inducing aversion Luca Zangrandi, Johannes Burtscher and Christoph Schwarzer (Innsbruck)
15:00–15:30	Coffee break / Posters
	Oral Communications – Session 3
	Chair: Reiner Fischer-Colbrie (Innsbruck)
15:30–15:45 → A2.4	Transient receptor potential ankyrin 1 channels participate in somatic pain hypersensitivity in experimental colitis Piyush Jain, Romina Nassini, Serena Materazzi, Duccio Rossi Degl’Innocenti, Francesco De Logu, Camilla Fusi, Ahmed M. Hassan, Raphaela Mayerhofer, Florian Reichmann, Pierangelo Geppetti and Peter Holzer (Florence, Graz)
15:45–16:00 → X.14	Monoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptors and increased colonic opioid sensitivity Ulrike Taschler, Thomas O. Eichmann, Franz P. W. Radner, Gernot F. Grabner, Heimo Wolinski, Martin Storr, Achim Lass, Gunther Marsche, Ákos Heinemann, Rudolf Schicho and Robert Zimmermann (Graz, Munich)
16:00–16:15 → X.4	Role of TRPV1, substance P and NK₁ receptor genes in the botulinum toxin type A antinociceptive action in mice Ivica Matak, Valeria Tekus, Zdravko Lacković and Zsuzsanna Helyes (Zagreb, Pécs)
16:15–16:30 → A2.13	Oxidative phosphorylation in the healthy and in the epileptic mouse brain Johannes Burtscher, Luca Zangrandi, Erich Gnaiger and Christoph Schwarzer (Innsbruck)
16:30–17:00	Break
	Otto Loewi Memorial Lecture
17:00–18:30	Welcome Address: Josef Smolle (Rector, Medical University of Graz) Introduction and Chair: Ákos Heinemann (Graz) On the David Herzog Fonds: Peter Scherrer (Graz) Francesca Levi-Shaffer (Jerusalem, Israel) “The mast cells, the eosinophils and the allergic effector unit: the best pharmacological target for allergy” Organised by the Medical University of Graz and the David Herzog Fonds of the universities of Styria

	Welcome Reception
19:30	Reception by the Mayor of the City of Graz Town Hall, Hauptplatz 1 Free for registered participants