APHAR - Austrian Pharmacological Society - Österreichische Pharmakologische Gesellschaft

THURSDAY 19 Nov FRIDAY 20 Nov SATURDAY 21 Nov POSTERS 19−21 Nov
GENERAL INFORMATION HIGHLIGHTS SOCIAL PROGRAM TRAVEL & ACCOMODATION

15th Scientific Symposium of the
Austrian Pharmacological Society (APHAR)
Invited Guest Societies: Hungarian Society of Experimental and Clinical Pharmacology (MFT) and Slovenian Pharmacological Society (SDF)
Graz, 19–21 November 2009
POSTERS 19–21 NOV

Click on icon above for print version of programme

POSTER PRESENTATIONS

Presentation prizes:
• Prizes for Best Poster and Best Oral Presentations
sponsored by and
The prizes will be awarded at the end of the meeting.

Austrian Pharmacological Society (APHAR)
(*denotes presenting author; click on the abstract icon for the abstract preview)
A1 The targeting of US28 is dependent on GASP-1
Elisabeth Moser*, Pia Tschische, Wolfgang Platzer, Veronika Pommer, Dawn Thompson, Helmut Schaider, Lene Martini, Jennifer Whistler and Maria Waldhoer (Graz, San Francisco)
A2 Inhibitory effects of prostaglandin EP₄ receptors on human eosinophils
Petra Luschnig-Schratl*, Eva M. Sturm, Viktória Kónya, Rufina Schuligoi and Ákos Heinemann (Graz)
A3 GPR55: signaling pathways and functions
Nariman Balenga*, Ralf Schröder, Julia Kargl, Wolfgang Platzer, Stefanie Blättermann, Ákos Heinemann, Evi Kostenis and Maria Waldhoer (Graz, Bonn)
A4 The sorting protein GASP-1 regulates the constitutive signaling capacity of the virally encoded chemokine receptor US28
Pia Tschische*, Elisabeth Moser , Dawn Thompson, Wolfgang Platzer, Henry Vischer, Martine J. Smit, Helmut Schaider, Lene Martini, Jennifer Whistler and Maria Waldhoer (Graz, San Francisco, Amsterdam)
A5 Interactions of the G protein-coupled receptor-associated sorting proteins (GASP) 1 and 2 with the novel cannabinoid receptor GPR55
Julia Kargl*, Nariman Balenga, Lene Martini, Jennifer Whistler and Maria Waldhoer (Graz, San Francisco)
A6 The effect of carbamylation on the functionality of high-density lipoprotein
Michael Holzer*, Martin Gauster, Ruth Birner-Grünberger and Gunther Marsche (Graz)
A8 Prostaglandin E₂ acts via the EP₄ receptor to inhibit platelet aggregation
Sonia Philipose*, Martina Ofner, Ákos Heinemann and Rufina Schuligoi (Graz)
A10 Endothelial prostaglandin I₂ restrains eosinophil trafficking
Viktória Kónya*, Eva M. Sturm, Annarita Graziani and Ákos Heinemann (Graz)
A13 The gut–mood axis: a novel role of the gut hormone peptide YY on emotional-affective behaviour in mice
Evelin Painsipp*, Herbert Herzog and Peter Holzer (Graz, Sydney)
A14 Characterization of receptors involved in serotonin contractions of isolated human umbilical artery in uncomplicated pregnancy
Miroslav Radenković*, Nebojša Radunović, Paja Momčilov and Leposava Grbović (Belgrade)
A15 Modification of actin fibers changes the electrical phenotype of cardiac myofibroblasts
Christian Rosker*, Nicolò Salvarani and Stephan Rohr (Bern)
A16 In vitro and in vivo profiling of P-glycoprotein in human neuroblastoma and rhabdomyosarcoma cells under simvastatin exposure
Evelyn Sieczkowski*, Peter Ambros and Martin Hohenegger (Vienna)
A17 Nucleotides excite sensory neurons via two P2Y receptors and a dual signaling cascade
Arsalan Yousuf* and Stefan Boehm (Vienna)
A18 P2Y₁ receptors are linked to K_Ca2 channels in PC12 cells
Klaus Schicker* and Stefan Boehm (Vienna)
A20 L-type voltage-gated calcium channels in hippocampal neurons and their potential as anti-epilept(ogen)ic drug targets
Petra Geier*, Michael Lagler, Stefan Boehm and Helmut Kubista (Vienna)
A22 3,5-Di-t-butyl catechol (DTCAT) as an activator of the human skeletal muscle ryanodine receptor Ca²⁺ channel and its evaluation as a test substance for the assessment of susceptibility to malignant hyperthermia
Caterina Lacava, Andrea Michalek-Sauberer, Birgit Kraft, Giampietro Sgaragli, Elisabeth Sipos, Carmen Höller, Hans-Georg Kress, Fabio Fusi and Lukas G. Weigl* (Vienna, Siena)
A24 From frog oocytes to mammalian cells: substantial differences in modulation of Na_V1.4 channel slow kinetic behaviour by the β1 subunit
Péter Lukács*, René Cervenka, Touran Zarrabi, Xaver König, Karlheinz Hilber and Hannes Todt (Vienna)
A25 Double mutant gating perturbation analysis predicts a high conformational stability of the domain IV S6 segment of the voltage-gated Na⁺ channel
René Cervenka*, Touran Zarrabi, Péter Lukács, Xaver König, Karlheinz Hilber and Hannes Todt (Vienna)
A26 Attenuation by a novel synthetic analogue of ACTH_4–7 of the learning and memory deficits in juvenile rats treated with amphetamine in utero: role of nitric oxide
Valentina Bashkatova*, Sergey Sudakov, Darya Rezvanova, Helmut Prast and Anatoly Vanin (Moscow, Innsbruck)
A27 Importance of the carboxyl terminus for folding and trafficking of the serotonin transporter
Ali El-Kasaby*and Oliver Kudlacek (Vienna)
A28 Cytokine signalling in human melanoma cells determines susceptability to statin-induced apoptosis
Christoph Minichsdorfer*and Martin Hohenegger (Vienna)
A29 Unexpected role of STAT1 serine727 for NK cell function
Eva M. Putz*, Eva Zebedin, Agnes Csiszar, Michaela Prchal, Angelika Berger, Thomas Decker, Pavel Kovarik and Veronika Sexl (Vienna)
A30 Regulation of CFTR expression and function by NOS isoforms
Christina Glöckel*, Xaver König, Herwig Just and Michael Freissmuth (Vienna)
A32 A_2A adenosine receptor interacting partners (interactome)
Ingrid Gsandtner*, Simon Keuerleber, Patrick Thurner and Oliver Kudlacek (Vienna)
A33 The role of NPY in expression and extinction of conditioned fear
Dilip Verma, Ramon O. Tasan*, Herbert Herzog and Günther Sperk (Innsbruck, Sydney)
A34 Protein kinase C-ζ is involved in the inhibition of eosinophil migration
Eva M. Sturm*, Gerald P. Parzmair, Petra Luschnig-Schratl, Viktória Kónya and Ákos Heinemann (Graz)
A35 Bioavailability of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides after oral administration in rats and distribution in various tissues
Karin Wölkart*, Reginald Frye, Hartmut Derendorf, Veronika Butterweck and Rudolf Bauer (Graz, Gainesville)
A36 Absolute and relative bioavailabilities of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides after intravenous and oral single doses in rats
Karin Wölkart*, Reginald Frye, Hartmut Derendorf, Veronika Butterweck and Rudolf Bauer (Graz, Gainesville)
A37 A relationship between membrane permeability of amphetamines and serotonin efflux via serotonin transporters
Walter Sandtner*, Klaus Gerstbrein and Harald H. Sitte (Vienna)
A38 Active metabolites formed during hepatic first-pass: simulations featuring their contribution to the overall effect in altered liver clearance and drug-drug interactions
Ahmed M. Abdelaziz*, Mohammad al-Araby, Laila Mahran, Hilde Spahn-Langguth (Cairo, Graz)
A39 Endogenous dynorphin in emotional control and stress response
Christoph Schwarzer*, Walter Wittmann, Eduard Schunk, Iris Kastenberger, Stefano Gaburro, Nicolas Singewald and Herbert Herzog (Innsbruck, Sydney)
A40 Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2
Matteo Beretta*, Antonius C.F. Gorren, Verena M. Wenzl, Robert Weis, Michael Russwurm, Doris Koesling, Kurt Schmidt and Bernd Mayer (Graz, Bochum)

APHAR Section of Clinical Pharmacology
(*denotes presenting author; click on the abstract icon for the abstract preview)
(Abstracts K1–K10 will not be published)
K1 In vitro and in vivo activity of sphingosine kinase 1 LNA oligonucleotides in gastric cancer
Thorsten Füreder*, Doris Hoeflmayer, Agnes Jaeger-Lansky, Bo Hansen and Volker Wacheck (Vienna, Hørsholm)
K3 Effects of moxaverine on ocular blood flow in patients with age-related macular degeneration, patients with primary open angle glaucoma and in healthy controls
Doreen Schmidl*, Berthold Pemp, Gerhard Garhöfer, Michael Lasta and Leopold Schmetterer (Vienna)
K6 Blockade of the renin-angiotensin system by the angiotensin-converting enzyme inhibitor ramipril alters gene expression in skeletal muscle in healthy subjects
Martin Brunner*, Wolfgang M. Schmidt, Robert Sauermann, Michael Krebs and Markus Müller (Vienna)
K9 Proof of concept for the anti-von Willebrand factor aptamer ARC1779 in patients with acute thrombotic thrombocytopenic purpura (TTP)
Bernd Jilma*, Eva-Luise Hobl, Petra Jilma, Jim Gilbert, Renta Hutabarat, Monika Gorczyca, Paul Knöbl (Vienna; Cambridge, MA)
K10 Proof of concept for the anti-von Willebrand factor aptamer ARC1779 in a patient with familial thrombotic thrombocytopenic purpura (TTP)
Eva-Luise Hobl*, Monika Gorczyca, Bernd Jilma, Jim Gilbert, Renta Hutabarat and Paul Knöbl (Vienna; Cambridge, MA)

Hungarian Society for Experimental and Clinical Pharmacology (MFT)
(*denotes presenting author; click on the abstract icon for the abstract preview)
A41 A single neurotoxic dose of MDMA decreases BDNF expression in the frontoparietal cortex but not in the hippocampus
Szilvia Vas*, Diána Kostyalik, Csaba Ádori, Rómeó D. Andó and György Bagdy (Budapest)
A43 Characterization of different G protein coupling properties of CB₁ and CB₂ cannabinoid receptors and GPR55 receptor using BRET
Pál Gyombolai*, Gábor Turu and László Hunyady (Budapest)
A44 Electrophysiological characteristics of heart ventricular papillary muscles in diabetic histidine decarboxylase knockout and wild-type mice
Andrea Szebeni*, András Falus and Valéria Kecskeméti (Budapest)
A45 Analysis of sleep EEG during rebound sleep after three days REM deprivation
Diána Kostyalik*, Szilvia Vas, Tamás Kitka, Zita Kátai and György Bagdy (Budapest)
A47 Behavioural sensitisation of rat dams treated with morphine pre- and postpartum
Melinda Sobor*, Julia Timár, Susanna Gyarmati and Susanna Fürst (Budapest)
A49 The electrophysiological and hemodynamical effects of pyruvate on diabetic and control rat hearts
Gábor Bárdi*, Katarina Csoltkova, László Károlyi, Andrea Szebeni and Valéria Kecskeméti (Budapest)
A51 Transactivation within the AT₁ angiotensin receptor homodimer: the role of the conserved DRY motif
Bence Szalai*, Péter Várnai and László Hunyady (Budapest)
A54 Role of sensory neurons on pancreatic beta cell function and on development of insulin resistance
Barna Peitl*, Róbert Döbrönte, László Drimba, Réka Sári, József Németh and Zoltán Szilvássy (Debrecen)

Slovenian Pharmacological Soceity (SDF)
(*denotes presenting author; click on the abstract icon for the abstract preview)
A55 Cardioprotective effects of bilberry extract on ischemia-reperfusion-induced injury in isolated rat heart
Lovro Žiberna*, Mojca Lunder, Špela Može, Andreja Vanzo and Gorazd Drevenšek (Ljubljana)
A56 Presence of bilitranslocase in the vascular system and its role in the vasodilatation activity of anthocyanins
Lovro Žiberna*, Mojca Lunder, Špela Može, Gorazd Drevenšek and Sabina Passamonti (Ljubljana, Trieste)
A57 Cellular antioxidant activity of bilirubin in the human endothelial cell line EA.hy 926 is mediated by bilitranslocase
Lovro Žiberna*, Federica Tramer and Sabina Passamonti (Ljubljana, Trieste)
A58 Sertraline and amitriptyline enhance histamine metabolism in guinea-pig tissues
Simona Rajtar* and Tatjana Irman-Florjanc (Ljubljana)
A62 Cardiotoxic activity of polymeric 3-alkylpyridinium salts from the marine sponge Reniera sarai
Mojca Lunder*, Lovro Žiberna, Kristina Sepčić and Gorazd Drevenšek (Ljubljana)
A63 The preventive cardiovascular effect of a combination of statin and angiotensin receptor blocker at sub-therapeutic doses in middle-aged healthy volunteers
Petra Šinigoj*, Mojca Lunder, Martin Šinigoj, Gorazd Drevenšek and Mišo Šabovič (Ljubljana)
A64 Endothelin-1 increases osteoclastic bone resorption via endothelin A receptors during orthodontic tooth movement in rats
Špela Sprogar*, Alja Meh, Tomaž Vaupotič, Andrej Cör, Martina Drevenšek and Gorazd Drevenšek (Ljubljana, Koper)
A65 The effect of cetirizine, an H₁ receptor antagonist, on bone modeling during orthodontic tooth movement in rats
Alja Meh*, Špela Sprogar, Janja Marc, Andrej Cör, Gorazd Drevenšek and Martina Drevenšek (Ljubljana)

_________
21.11.2009

THURSDAY 19 Nov	FRIDAY 20 Nov	SATURDAY 21 Nov	POSTERS 19−21 Nov
GENERAL INFORMATION	HIGHLIGHTS	SOCIAL PROGRAM	TRAVEL & ACCOMODATION

POSTER PRESENTATIONS
Presentation prizes: • Prizes for Best Poster and Best Oral Presentations sponsored by and The prizes will be awarded at the end of the meeting.
Austrian Pharmacological Society (APHAR)
(denotes presenting author; click on the abstract icon for the abstract preview)*
A1	The targeting of US28 is dependent on GASP-1 Elisabeth Moser, Pia Tschische, Wolfgang Platzer, Veronika Pommer, Dawn Thompson, Helmut Schaider, Lene Martini, Jennifer Whistler and Maria Waldhoer* (Graz, San Francisco)
A2	Inhibitory effects of prostaglandin EP₄ receptors on human eosinophils Petra Luschnig-Schratl, Eva M. Sturm, Viktória Kónya, Rufina Schuligoi and Ákos Heinemann* (Graz)
A3	GPR55: signaling pathways and functions Nariman Balenga, Ralf Schröder, Julia Kargl, Wolfgang Platzer, Stefanie Blättermann, Ákos Heinemann, Evi Kostenis and Maria Waldhoer* (Graz, Bonn)
A4	The sorting protein GASP-1 regulates the constitutive signaling capacity of the virally encoded chemokine receptor US28 Pia Tschische, Elisabeth Moser , Dawn Thompson, Wolfgang Platzer, Henry Vischer, Martine J. Smit, Helmut Schaider, Lene Martini, Jennifer Whistler and Maria Waldhoer* (Graz, San Francisco, Amsterdam)
A5	Interactions of the G protein-coupled receptor-associated sorting proteins (GASP) 1 and 2 with the novel cannabinoid receptor GPR55 Julia Kargl, Nariman Balenga, Lene Martini, Jennifer Whistler and Maria Waldhoer* (Graz, San Francisco)
A6	The effect of carbamylation on the functionality of high-density lipoprotein Michael Holzer, Martin Gauster, Ruth Birner-Grünberger and Gunther Marsche* (Graz)
A8	Prostaglandin E₂ acts via the EP₄ receptor to inhibit platelet aggregation Sonia Philipose, Martina Ofner, Ákos Heinemann and Rufina Schuligoi* (Graz)
A10	Endothelial prostaglandin I₂ restrains eosinophil trafficking Viktória Kónya, Eva M. Sturm, Annarita Graziani and Ákos Heinemann* (Graz)
A13	The gut–mood axis: a novel role of the gut hormone peptide YY on emotional-affective behaviour in mice Evelin Painsipp, Herbert Herzog and Peter Holzer* (Graz, Sydney)
A14	Characterization of receptors involved in serotonin contractions of isolated human umbilical artery in uncomplicated pregnancy Miroslav Radenković, Nebojša Radunović, Paja Momčilov and Leposava Grbović* (Belgrade)
A15	Modification of actin fibers changes the electrical phenotype of cardiac myofibroblasts Christian Rosker, Nicolò Salvarani and Stephan Rohr* (Bern)
A16	In vitro and in vivo profiling of P-glycoprotein in human neuroblastoma and rhabdomyosarcoma cells under simvastatin exposure Evelyn Sieczkowski, Peter Ambros and Martin Hohenegger* (Vienna)
A17	Nucleotides excite sensory neurons via two P2Y receptors and a dual signaling cascade Arsalan Yousuf and Stefan Boehm* (Vienna)
A18	P2Y₁ receptors are linked to K_Ca2 channels in PC12 cells Klaus Schicker and Stefan Boehm* (Vienna)
A20	L-type voltage-gated calcium channels in hippocampal neurons and their potential as anti-epilept(ogen)ic drug targets Petra Geier, Michael Lagler, Stefan Boehm and Helmut Kubista* (Vienna)
A22	3,5-Di-t-butyl catechol (DTCAT) as an activator of the human skeletal muscle ryanodine receptor Ca²⁺ channel and its evaluation as a test substance for the assessment of susceptibility to malignant hyperthermia Caterina Lacava, Andrea Michalek-Sauberer, Birgit Kraft, Giampietro Sgaragli, Elisabeth Sipos, Carmen Höller, Hans-Georg Kress, Fabio Fusi and Lukas G. Weigl* (Vienna, Siena)
A24	From frog oocytes to mammalian cells: substantial differences in modulation of Na_V1.4 channel slow kinetic behaviour by the β1 subunit Péter Lukács, René Cervenka, Touran Zarrabi, Xaver König, Karlheinz Hilber and Hannes Todt* (Vienna)
A25	Double mutant gating perturbation analysis predicts a high conformational stability of the domain IV S6 segment of the voltage-gated Na⁺ channel René Cervenka, Touran Zarrabi, Péter Lukács, Xaver König, Karlheinz Hilber and Hannes Todt* (Vienna)
A26	Attenuation by a novel synthetic analogue of ACTH_4–7 of the learning and memory deficits in juvenile rats treated with amphetamine in utero: role of nitric oxide Valentina Bashkatova, Sergey Sudakov, Darya Rezvanova, Helmut Prast and Anatoly Vanin* (Moscow, Innsbruck)
A27	Importance of the carboxyl terminus for folding and trafficking of the serotonin transporter Ali El-Kasabyand Oliver Kudlacek* (Vienna)
A28	Cytokine signalling in human melanoma cells determines susceptability to statin-induced apoptosis Christoph Minichsdorferand Martin Hohenegger* (Vienna)
A29	Unexpected role of STAT1 serine727 for NK cell function Eva M. Putz, Eva Zebedin, Agnes Csiszar, Michaela Prchal, Angelika Berger, Thomas Decker, Pavel Kovarik and Veronika Sexl* (Vienna)
A30	Regulation of CFTR expression and function by NOS isoforms Christina Glöckel, Xaver König, Herwig Just and Michael Freissmuth* (Vienna)
A32	A_2A adenosine receptor interacting partners (interactome) Ingrid Gsandtner, Simon Keuerleber, Patrick Thurner and Oliver Kudlacek* (Vienna)
A33	The role of NPY in expression and extinction of conditioned fear Dilip Verma, Ramon O. Tasan, Herbert Herzog and Günther Sperk* (Innsbruck, Sydney)
A34	Protein kinase C-ζ is involved in the inhibition of eosinophil migration Eva M. Sturm, Gerald P. Parzmair, Petra Luschnig-Schratl, Viktória Kónya and Ákos Heinemann* (Graz)
A35	Bioavailability of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides after oral administration in rats and distribution in various tissues Karin Wölkart, Reginald Frye, Hartmut Derendorf, Veronika Butterweck and Rudolf Bauer* (Graz, Gainesville)
A36	Absolute and relative bioavailabilities of dodeca-2E,4E,8E,10E/Z-tetraenoic acid isobutylamides after intravenous and oral single doses in rats Karin Wölkart, Reginald Frye, Hartmut Derendorf, Veronika Butterweck and Rudolf Bauer* (Graz, Gainesville)
A37	A relationship between membrane permeability of amphetamines and serotonin efflux via serotonin transporters Walter Sandtner, Klaus Gerstbrein and Harald H. Sitte* (Vienna)
A38	Active metabolites formed during hepatic first-pass: simulations featuring their contribution to the overall effect in altered liver clearance and drug-drug interactions Ahmed M. Abdelaziz, Mohammad al-Araby, Laila Mahran, Hilde Spahn-Langguth* (Cairo, Graz)
A39	Endogenous dynorphin in emotional control and stress response Christoph Schwarzer, Walter Wittmann, Eduard Schunk, Iris Kastenberger, Stefano Gaburro, Nicolas Singewald and Herbert Herzog* (Innsbruck, Sydney)
A40	Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2 Matteo Beretta, Antonius C.F. Gorren, Verena M. Wenzl, Robert Weis, Michael Russwurm, Doris Koesling, Kurt Schmidt and Bernd Mayer* (Graz, Bochum)
APHAR Section of Clinical Pharmacology
(denotes presenting author; click on the abstract icon for the abstract preview)* (Abstracts K1–K10 will not be published)
K1	In vitro and in vivo activity of sphingosine kinase 1 LNA oligonucleotides in gastric cancer Thorsten Füreder, Doris Hoeflmayer, Agnes Jaeger-Lansky, Bo Hansen and Volker Wacheck* (Vienna, Hørsholm)
K3	Effects of moxaverine on ocular blood flow in patients with age-related macular degeneration, patients with primary open angle glaucoma and in healthy controls Doreen Schmidl, Berthold Pemp, Gerhard Garhöfer, Michael Lasta and Leopold Schmetterer* (Vienna)
K6	Blockade of the renin-angiotensin system by the angiotensin-converting enzyme inhibitor ramipril alters gene expression in skeletal muscle in healthy subjects Martin Brunner, Wolfgang M. Schmidt, Robert Sauermann, Michael Krebs and Markus Müller* (Vienna)
K9	Proof of concept for the anti-von Willebrand factor aptamer ARC1779 in patients with acute thrombotic thrombocytopenic purpura (TTP) Bernd Jilma, Eva-Luise Hobl, Petra Jilma, Jim Gilbert, Renta Hutabarat, Monika Gorczyca, Paul Knöbl* (Vienna; Cambridge, MA)
K10	Proof of concept for the anti-von Willebrand factor aptamer ARC1779 in a patient with familial thrombotic thrombocytopenic purpura (TTP) Eva-Luise Hobl, Monika Gorczyca, Bernd Jilma, Jim Gilbert, Renta Hutabarat and Paul Knöbl* (Vienna; Cambridge, MA)
Hungarian Society for Experimental and Clinical Pharmacology (MFT)
(denotes presenting author; click on the abstract icon for the abstract preview)*
A41	A single neurotoxic dose of MDMA decreases BDNF expression in the frontoparietal cortex but not in the hippocampus Szilvia Vas, Diána Kostyalik, Csaba Ádori, Rómeó D. Andó and György Bagdy* (Budapest)
A43	Characterization of different G protein coupling properties of CB₁ and CB₂ cannabinoid receptors and GPR55 receptor using BRET Pál Gyombolai, Gábor Turu and László Hunyady* (Budapest)
A44	Electrophysiological characteristics of heart ventricular papillary muscles in diabetic histidine decarboxylase knockout and wild-type mice Andrea Szebeni, András Falus and Valéria Kecskeméti* (Budapest)
A45	Analysis of sleep EEG during rebound sleep after three days REM deprivation Diána Kostyalik, Szilvia Vas, Tamás Kitka, Zita Kátai and György Bagdy* (Budapest)
A47	Behavioural sensitisation of rat dams treated with morphine pre- and postpartum Melinda Sobor, Julia Timár, Susanna Gyarmati and Susanna Fürst* (Budapest)
A49	The electrophysiological and hemodynamical effects of pyruvate on diabetic and control rat hearts Gábor Bárdi, Katarina Csoltkova, László Károlyi, Andrea Szebeni and Valéria Kecskeméti* (Budapest)
A51	Transactivation within the AT₁ angiotensin receptor homodimer: the role of the conserved DRY motif Bence Szalai, Péter Várnai and László Hunyady* (Budapest)
A54	Role of sensory neurons on pancreatic beta cell function and on development of insulin resistance Barna Peitl, Róbert Döbrönte, László Drimba, Réka Sári, József Németh and Zoltán Szilvássy* (Debrecen)
Slovenian Pharmacological Soceity (SDF)
(denotes presenting author; click on the abstract icon for the abstract preview)*
A55	Cardioprotective effects of bilberry extract on ischemia-reperfusion-induced injury in isolated rat heart Lovro Žiberna, Mojca Lunder, Špela Može, Andreja Vanzo and Gorazd Drevenšek* (Ljubljana)
A56	Presence of bilitranslocase in the vascular system and its role in the vasodilatation activity of anthocyanins Lovro Žiberna, Mojca Lunder, Špela Može, Gorazd Drevenšek and Sabina Passamonti* (Ljubljana, Trieste)
A57	Cellular antioxidant activity of bilirubin in the human endothelial cell line EA.hy 926 is mediated by bilitranslocase Lovro Žiberna, Federica Tramer and Sabina Passamonti* (Ljubljana, Trieste)
A58	Sertraline and amitriptyline enhance histamine metabolism in guinea-pig tissues Simona Rajtar and Tatjana Irman-Florjanc* (Ljubljana)
A62	Cardiotoxic activity of polymeric 3-alkylpyridinium salts from the marine sponge Reniera sarai Mojca Lunder, Lovro Žiberna, Kristina Sepčić and Gorazd Drevenšek* (Ljubljana)
A63	The preventive cardiovascular effect of a combination of statin and angiotensin receptor blocker at sub-therapeutic doses in middle-aged healthy volunteers Petra Šinigoj, Mojca Lunder, Martin Šinigoj, Gorazd Drevenšek and Mišo Šabovič* (Ljubljana)
A64	Endothelin-1 increases osteoclastic bone resorption via endothelin A receptors during orthodontic tooth movement in rats Špela Sprogar, Alja Meh, Tomaž Vaupotič, Andrej Cör, Martina Drevenšek and Gorazd Drevenšek* (Ljubljana, Koper)
A65	The effect of cetirizine, an H₁ receptor antagonist, on bone modeling during orthodontic tooth movement in rats Alja Meh, Špela Sprogar, Janja Marc, Andrej Cör, Gorazd Drevenšek and Martina Drevenšek* (Ljubljana)